apc cd49f α6 integrin (Thermo Fisher)
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86
Structured Review
Thermo Fisher
apc cd49f α6 integrin
Apc Cd49f α6 Integrin, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/apc+cd49f+%CE%B16+integrin/pmc03656088-41-31-32?v=Thermo+Fisher
Average 86 stars, based on 1 article reviews
Apc Cd49f α6 Integrin, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/apc+cd49f+%CE%B16+integrin/pmc03656088-41-31-32?v=Thermo+Fisher
Average 86 stars, based on 1 article reviews
apc cd49f α6 integrin - by Bioz Stars,
2026-08
86/100 stars
Images
1) Product Images from "Highly Upregulated Lhx2 in the Foxn1 −/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche"
Article Title: Highly Upregulated Lhx2 in the Foxn1 −/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
Journal: PLoS ONE
doi: 10.1371/journal.pone.0064223
Figure Legend Snippet: CD49f/α6-integrin (blue) positive epithelium dominates within the basal layer of the surface epithelium. CD200 (purple) and CD34 (red) are both strongly expressed within the bulge region. In addition, CD200 is also expressed in upper parts of the outer root sheet (ORS) whereas CD34 expression may extend below the bulge region. Matrix cells of the hair bulb are considered CD49f/CD200/CD34 negative. In general, surface markers of epithelial progeny are not exclusive for each other in part depending on the stage of hair cycling. This study evaluates various effects of Foxn1 loss-of-function on telogen-anagen hair cycling and epithelial stem cell niche regulation in Nu/Nu mice.
Techniques Used: Expressing
Figure Legend Snippet: (A) Flow cytometry summary table listing fractions positive for markers of progeny within epithelial isolates from newborns (%±SD, n>6). Distinct differences between the Foxn1 −/− phenotype and wild type are demonstrated by comparative sample flow cytometry data gated for (B) CD49f, CD34, CD200 and (C) Oct3/4 positive epithelial fractions.
Techniques Used: Flow Cytometry
Figure Legend Snippet: (A) Newborn epithelial isolates on day one post birth (NBD1) of Foxn1 −/− background show strong upregulation of Lhx2 which is not maintained following three days of in vitro culture along with other marker genes of progeny (ND = non-detectable). (B) However, CD200 levels remain higher in cultured Foxn1 −/− isolates compared to WT (qPCR/ΔΔCt-method: n = 4; *P<0.05, ↓P<0.05). (C) Flow cytometry on day 5 of in vitro cultures reveals a shift from a dominant CD49f++ subpopulation in vivo in favor of a CD34+/CD49f+ positive epithelial subpopulation in vivo which is more pronounced in Nu/Nu isolates vs. WT.
Techniques Used: In Vitro, Marker, Cell Culture, Flow Cytometry, In Vivo
